Well the best thing you can do is apply the general principles you learn on here about handling panic attacks (challenging your thoughts, etc.) in any situation. I am about to fly cross-country on Saturday and I'm a little nervous about it, too. Last time, though, I did ok by challenging my thoughts and reminding myself that I can't pass out or die from a panic attack, no matter how much it feels like it. So if I do have a major panic attack when flying this weekend I'll just try to remember those things. Also, sometimes the feeling that I'm going to pass out goes away if I just think to myself "fine - go ahead and pass out! what do I care?! i'm in a seat and it will just look like i went to sleep so i won't look like a weirdo. it's not fun, but it's not the end of the world - so if you're going to pass out, just go ahead and do it!" That almost always works. It's like it takes all the fun out of it for the panic attack so it goes away =). I know - I'm weird. :) But it works for me!