I started out on Effexor, and was tempted to stop it many times. I had every single side effect listed on the label except for the vision problems. After a few weeks of feeling like I was dying, my doctor took me off of that and put me on Zoloft. Switching meds was the worse feeling in the world for me. Not only did I have to deal with the side effects of coming off of a drug, but I had to deal with the side effects for coming on a new drug. Thankfully I have reacted to the Zoloft better, and I'm not feeling any side effects. I've been on the zoloft for a few months now. There will be times when I forget to take it for a day or so, and I can really tell the change in my mood. I get all cranky and just want to bite everyone's head off. but as soon as I take the Zoloft, I'm much better, and my husband can actually live with me without fearing for his life!