I have refractory double depression (treatment resistant dysthymia and major depression) and Generalized Anxiety Disorder and have been on most of the SSRIs only. Some have worked, some not. Also take Klonopin or anxiety. Right now I'm on Wellbutrin 450 mg a day and Lexapro 30 mg a day, and they're not working. My doc had me try adding low dose Seroquel because he thinks the anxiety is my version of bipolar 2 (!). The Seroquel (50 mg) worked great for everything, but had the terrible side effect of difficult swallowing, among others, like sore throat, flu-like symptoms. Has anyone else had this problem with Seroquel and has it gone away? I stopped the pills about a week ago and I still have the problem.
Thanks.