I was on Effexor for 3 1/2 months, gradually building up to 300mg per day. I was on 300mg per day for 8 weeks and it did nothing. Since taking Effexor I did have trouble sleeping. My psychiatrist gave me Seroquel and Remeron which I take 1 hour before I go to bed. Once in bed I pass out instantly and I sleep for about 5 hours. I love those five hours as it is only peace I get. I now take Cipralex.
My doctor increased my dose to 300mg of Effexor 5 weeks ago. Most people that I have heard about are not on that high of dosage. My specialist said that at 225 not just serotonin is affected but norepiphrine. Now at 300 dopamine gets affected. I do notice more energy now but an still having a lot of problems with my mood. I am not sleeping well either.